Does lifting weights help your brain?

It may help a little: small gains in some thinking-test scores in older adults, but a noticeable benefit is uncertain, and several bias-corrected estimates are near zero.

By the Helibrain team Reviewed by Robert, biophysics PhD candidate Last checked: 31 October 2026 6 min read

A woman in a green T-shirt squats with a loaded barbell across her shoulders in a small home gym.

Short answer

Strength training may improve some thinking-test scores in older adults by a small amount, but a noticeable benefit is uncertain. Across 13 trials in adults over 50, the average gain was small (SMD = 0.29). In healthy older adults, it slightly improved executive function, the skills for planning, focus and switching tasks (g = 0.23). A 2026 preprint that corrected for publication bias found only an imprecise positive signal, for general thinking in healthy older adults; memory and executive function were near zero.

Evidence

Low for a noticeable gain in thinking-test scores; Moderate certainty of any effect. Estimated size: small (SMD = 0.29). Results differ by outcome and analysis: several bias-corrected estimates are near zero, and a careful 2026 trial missed its main goal.

One thing to do today

Do a full-body strength session of about 45 minutes with weights, bands or your body weight, starting light if you are new, and aim for twice a week. The WHO advises strength work on 2 or more days a week for general health; count any brain effect as a bonus.

Contents7 sections

What the research shows
How to use it
Where the evidence is weak
Is lifting better for your brain than cardio?
Does it help if your memory is already slipping?
Does lifting help with depression?
Try it in Helibrain

Lifting to stay sharp as you age? This is for you.

Two pairs of overlapping bell curves: with g = 0.23 the strength-training and comparison groups overlap a lot; with g = 0.76 the shift is larger. — **Figure 1.** What a small effect looks like: score spreads of two groups, shifted by the effect size (bell-shaped scores with equal spread assumed). Sources: Chen 2026 [1]; Molloy 2026 [2].

What the research shows

A 2018 review of exercise trials in adults over 50, with or without memory problems, found a small gain from strength training (SMD = 0.29, range 0.13 to 0.44, from 13 trials), using a model that handles several scores from one trial.
A 2026 review of 50 exercise trials in healthy older adults found a small gain in executive function from strength training (g = 0.23), using a model that handles several scores from one trial. Across all exercise types, it found signs of publication bias.
A 2026 review of 17 strength-training studies, not all randomised, in healthy adults (average age 67) found small gains in executive function, working memory and processing speed (g = 0.29, 0.37 and 0.27), a larger, more variable gain in overall scores (0.76) and no clear change in recall (−0.19, not significant). It counted several scores per study as separate results, so it may look more precise than it is.
A 2025 umbrella review of 133 reviews, all ages, healthy and ill, reported strength-training gains of 0.13 for memory to 0.31 for executive function. A 2026 preprint, not yet peer reviewed, re-analysed its trials with a correction for publication bias. Of its 10 strength-training subgroups, only general thinking (an overall score that combines several thinking skills, often from a short screening test) in healthy older adults stayed positive, and the estimate was imprecise (0.49 or 0.65, depending on the model, from 6 results in 3 reviews); a new study could still find no effect. In other groups, general thinking ranged from −0.17 to 0.51, depending on the group and model. Memory (−0.10 to 0.13) and executive function (−0.07 to 0.13) were near zero in every group. Treat these as context, not as the main estimate.
The 2026 AGUEDA trial randomised 90 cognitively normal adults (average age 71.8) to usual activity or, for 46 of them, three 60-minute strength sessions a week for 24 weeks. The main executive-function score did not beat control (SMD = 0.13, p = 0.37); a secondary attention-and-inhibition score did (SMD = 0.43).
In a 12-month trial with 155 women aged 65–75, lifting once or twice a week improved Stroop test scores by 12.6% and 10.9%, versus 0.5% worse with balance-and-tone exercise; set shifting and working memory did not differ.

Dot-and-range chart of strength-training effects on thinking-test scores, before and after bias correction. — **Figure 2.** Strength-training effects in mostly older adults, each with its 95% range. The bias-corrected rows come from a preprint and are context: general thinking stayed positive but imprecise; memory and executive function were near zero. Sources: Northey 2018 [21]; Chen 2026 [1]; Molloy 2026 [2]; Bartoš 2026 preprint [3].

How to use it

Work all major muscle groups at moderate or higher effort on 2 or more days a week. Older adults should include balance and strength work on 3 or more days a week.
Think in months: programmes in the 17-study review ran 8 to 24 weeks, two or three times a week.
You don't need maximal loads. In a small trial of 62 men aged 65–75, 50% and 80% of the one-lift maximum had "equally beneficial effects on cognitive functioning"; the trial was too small to prove equality.
Don't count on memory gains. Recall did not clearly improve in one review or after bias correction, though a 2-year follow-up of the 155-women trial found better memory with twice-weekly lifting (d = 0.45).

A week with two example strength days of about 45 minutes, and a timeline of 8 to 24 weeks. — **Figure 3.** A week and a few months of strength training, as the guidance and the trials describe them. Sources: WHO guidelines, Bull 2020 [7]; Molloy 2026 [2].

Where the evidence is weak

Bias correction shrinks some estimates. Across common exercise types in healthy people, a 2023 umbrella review's small gain (d = 0.22) fell to almost nothing (d = 0.05, inconclusive) after allowing for unpublished null studies.
Gains are smaller against active control groups. In the 50-trial review, all exercise types together beat active controls such as stretching by only g = 0.08, not significant.
Younger adults are missing. In a 2019 review, 23 of 24 studies had an average age of 50 or more, and results varied hugely (I² = 93%).
Children's evidence is preliminary. A review of 10 school-age studies, half combining strength with cardio, found a small gain across thinking, school results and on-task behaviour combined (SMD = 0.19).

Is lifting better for your brain than cardio?

There is no clear winner. A 2026 review in older adults without cognitive impairment found no clear difference between strength training and other exercise for executive function (low-certainty evidence). A 2023 umbrella review in adults aged 55 and older found small effects for both aerobic exercise (d = 0.17) and resistance exercise (d = 0.24, not significant, from two reviews).

Does it help if your memory is already slipping?

It's unclear, and these results are very uncertain. In Alzheimer's, Parkinson's or mild cognitive impairment, a 2026 network review ranked strength training first with a very large estimate from just a few trials (SMD = 1.50, from 3 trials; the review's own rating: low certainty), while another 2026 review of cognitive impairment or dementia found no significant effect (SMD = 0.36, p = 0.08, from 4 studies). Two trials against sham or balance exercise leaned positive: SMART, in 100 adults with mild cognitive impairment, though its effect range (−0.73 to 0.06) crossed zero, and a 12-month trial in 91 people with vascular cognitive impairment (0.18 units, of unknown everyday importance). If your memory keeps getting worse, talk to a clinician.

Does lifting help with depression?

It is unclear how much. In a 2024 network review of people whose depression was diagnosed or above a screening cut-off, strength training was linked to fewer symptoms than active controls (g = −0.49), but confidence in this result was very low.

Try it in Helibrain

Want to make strength training a habit? Add it to your plan in Helibrain for reminders and simple tracking. Curious about your own numbers? Take the free n-back test now and then, on the same device. Your scores show your own pattern, not a change in your brain.

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Sources

Chen W et al., 2026, BMC Public Health 26:1762. Effects of exercise on executive function in cognitively healthy older adults: a systematic review and three-level meta-analysis. doi.org/10.1186/s12889-026-27418-w
Molloy G et al., 2026, Ageing Research Reviews 121:103277. The effects of multi-session resistance exercise on cognitive function in healthy adults: a systematic research review and meta-analysis. doi.org/10.1016/j.arr.2026.103277
Bartoš F et al., 2026, PsyArXiv preprint v2 (not peer-reviewed in a journal; earlier version: IES Working Paper 31/2025). Effect of exercise on cognition, memory, and executive function: a study-level meta-meta-analysis across populations and exercise categories. doi.org/10.31234/osf.io/qr8e2_v2
Singh B et al., 2025, British Journal of Sports Medicine 59:866–876. Effectiveness of exercise for improving cognition, memory and executive function: a systematic umbrella review and meta-meta-analysis. doi.org/10.1136/bjsports-2024-108589
Fernandez-Gamez B et al., 2026, Alzheimer's & Dementia 22:e71019. Effect of a 24-week resistance exercise intervention on cognitive function in cognitively normal older adults: the AGUEDA randomized controlled trial. doi.org/10.1002/alz.71019
Liu-Ambrose T et al., 2010, Archives of Internal Medicine 170:170–178. Resistance training and executive functions: a 12-month randomized controlled trial. doi.org/10.1001/archinternmed.2009.494
Bull FC et al., 2020, British Journal of Sports Medicine 54:1451–1462. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. doi.org/10.1136/bjsports-2020-102955
Cassilhas RC et al., 2007, Medicine & Science in Sports & Exercise 39:1401–1407. The impact of resistance exercise on the cognitive function of the elderly. doi.org/10.1249/mss.0b013e318060111f
Best JR et al., 2015, Journal of the International Neuropsychological Society 21:745–756. Long-term effects of resistance exercise training on cognition and brain volume in older women: results from a randomized controlled trial. doi.org/10.1017/S1355617715000673
Ciria LF et al., 2023, Nature Human Behaviour 7:928–941. An umbrella review of randomized control trials on the effects of physical exercise on cognition. doi.org/10.1038/s41562-023-01554-4 (preprint with full methods: doi.org/10.1101/2022.02.15.480508)
Ciria LF et al., 2026, Nature Human Behaviour 10:2046. Author Correction: An umbrella review of randomized control trials on the effects of physical exercise on cognition (109 eligible studies, 100 analysed; estimates unchanged). doi.org/10.1038/s41562-026-02532-2
Landrigan JF et al., 2020 (online 2019), Psychological Research 84:1167–1183. Lifting cognition: a meta-analysis of effects of resistance exercise on cognition. doi.org/10.1007/s00426-019-01145-x
Jorquera-Cáceres I et al., 2026, Journal of the American Medical Directors Association 27:106427. Effects of resistance training on executive functions in community-dwelling older adults: a meta-analysis. doi.org/10.1016/j.jamda.2026.106427
Blomstrand P et al., 2023, European Review of Aging and Physical Activity 20:15. Mind body exercise improves cognitive function more than aerobic- and resistance exercise in healthy adults aged 55 years and older: an umbrella review. doi.org/10.1186/s11556-023-00325-4
Li X et al., 2026, Frontiers in Neurology 17:1877537. Comparative effects of six exercise modalities on global cognitive function in Alzheimer's disease, Parkinson's disease, and mild cognitive impairment: a systematic review and network meta-analysis. doi.org/10.3389/fneur.2026.1877537
Choe YH et al., 2026, Scientific Reports 16:19319. Effects of exercise modalities on cognitive and muscle function in older adults with cognitive impairment: a systematic review and meta-analysis. doi.org/10.1038/s41598-026-48294-9
Fiatarone Singh MA et al., 2014, Journal of the American Medical Directors Association 15:873–880 (erratum 2021, 22:479–481). The Study of Mental and Resistance Training (SMART) study: resistance training and/or cognitive training in mild cognitive impairment: a randomized, double-blind, double-sham controlled trial. doi.org/10.1016/j.jamda.2014.09.010
Liu-Ambrose T et al., 2026, Alzheimer's & Dementia 22:e71245. Resistance training and subcortical vascular cognitive impairment: a 12-month randomized trial. doi.org/10.1002/alz.71245
Noetel M et al., 2024, BMJ 384:e075847. Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials. doi.org/10.1136/bmj-2023-075847 (correction: doi.org/10.1136/bmj.q1024)
Robinson K et al., 2023, Sports Medicine 53:2095–2109. Effects of resistance training on academic outcomes in school-aged youth: a systematic review and meta-analysis. doi.org/10.1007/s40279-023-01881-6
Northey JM et al., 2018, British Journal of Sports Medicine 52:154–160. Exercise interventions for cognitive function in adults older than 50: a systematic review with meta-analysis. doi.org/10.1136/bjsports-2016-096587

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